Certain folders may have to be excluded from antivirus scanning when you use file-level antivirus software in SharePoint
Folders that may have to be excluded from antivirus scanning in SharePoint Note In the following sections, the placeholder Drive represents the letter of the drive on which you have your SharePoint application installed. Typically, this drive letter is C. SharePoint Foundation 2013 You may have to configure your antivirus software to exclude the following folders and subfolders from antivirus scanning: Drive :\Program Files\Common Files\Microsoft Shared\Web Server Extensions If you do not want to exclude the whole Web Server Extensions folder from antivirus scanning, you can exclude only the following two folders: Drive :\Program Files\Common Files\Microsoft Shared\Web Server Extensions\15\Logs Drive :\Program Files\Common Files\Microsoft Shared\Web Server Extensions\15\Data\Applications Note The Applications folder must be excluded only if the computer is running the SharePoint Foundation Search service. If the folder that contains the index file is located elsewhere, yo...